Have a look at: Low-level REST client status error:ava.lang.IllegalStateException: Request cannot be executed; I/O reactor status: STOPPED · Issue #42133 · elastic/elasticsearch (github.com)
and
Elasticsearch Request cannot be executed; I/O reactor status: STOPPED - Stack Overflow
It's worth checking on how many connections are being created from your client to ES, creating too many connections or not closing them properly can lead to this situation.