Randomly no response for search queries

We use elasticsearch since a couple of weeks and there are over 160 million
of entries separated in a couple of indexes splitted by month (e.g.
index_2014_01,index_2014_02,....).
Sometimes if we send a bulk query requests to the elasticsearch nodes for
some requests there is no responses and no timeouts. There is no chance to
reproduce this problem because it happens randomly and also on querys wich
worked seconds before with a minimum response time. We started to debug
down to the elasticsearch transport client without success. We noticed that
there was a request without response (Breakpoints where hooked in
response-listener, request-listener and failure-listener) - even after a
long wait time there was no response or failure. There is no exception or
log-output which indicates that problem except that after a time there is a
"disconnected from node" message. In the logs from the cluster-nodes there
is no error either.
There is not much load on the elasticsearch cluster and on our firewall all
ports from 9200 to 9400 are open

Our application structure:
TOMCAT 7 (JAVAEE-7u25) --> spring-data-elasticsearch-1.0.0.M2 -->
elasticsearch-1.1.0(1.0.0 with same issue) ----------> elasticsearch (8
nodes) version 1.0.0 (JAVA-7u25)

This issue happens randomly and we have no idea where it comes from.

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We noticed that after a few minutes a NodeDisconnectedException is thrown.

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