As a rule of thumb: if it's working for your server (you don't see a wall of exceptions), there's no difference in stability compared to the regular setup.
You might be able to work around those exceptions with some manual OSGi configuration: org.osgi.framework.bootdelegation=co.elastic.apm.agent.*
Where to add this varies based on the server and OSGi container. For some, there is already a file which already includes a list of packages. So search for bootdelegation in your server directory and add co.elastic.apm.agent.* to the existing list.
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