I don't know your particular data or how well this works on line charts, but here's a way to make the vertical bar chart have a different color for each bar;
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I start with the defautl Y-Axis aggregation of Count
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I add an X-Axis Terms aggregation on my extension.raw field. But the bars are all the same color;

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Now I "Add sub-buckets", "Split Bars" and do the exact same Terms aggregation on extension.raw again

And to split into 4 quadrants, there's 2 things you could try. You can add a sub-bucket and "Split Charts". Or you can make 4 specific charts and put them together on a Dashboard.
Regards,
Lee